CAS:394-68-3|8-fluoroquinoline

The primary application of 8-fluoroquinoline is as an intermediate in pesticide production. It is a pale yellow to colorless liquid, with a CAS number of 394-68-3 and a molecular formula of C9H6FN.

{{0}}FLUOROQUINOLINE is stable at room temperature and can be dissolved in organic solvents, such as alcohols and ketones. Its density is 1.215 g/cm³, and it has a boiling point of 148 degree at 30 Torr. The refractive index is 1.60, with a flash point ranging from 98.0±19.8 degree , and a vapor pressure of 0.1±0.5 mmHg at 25 degree .

Pesticide Synthesis: 8-fluoroquinoline is a crucial intermediate in the synthesis of specific fluoroquinoline pesticides. These pesticides are known for their high efficiency, low toxicity, and broad-spectrum effectiveness against insects, fungi, and weeds. They play a vital role in the prevention and control of crop diseases and pests.

Catalyst or Ligand: 8-fluoroquinoline can function as a ligand for metal catalysts, participating in various organic reactions, such as asymmetric catalytic reactions and cross-coupling reactions. This application improves the selectivity and efficiency of these reactions.

Synthetic Drug Intermediate: As a significant pharmaceutical intermediate, 8-fluoroquinoline is used to synthesize a variety of drugs, including antimalarial, antibacterial, and antiviral medications. For instance, it serves as a key starting material or intermediate in the synthesis of certain quinoline antibacterial drugs. By incorporating modifications like fluorine atoms, the activity and bioavailability of the drugs can be enhanced.

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